1,3,4-Oxadiazol-2(3H)-one,5-(4-pyridinyl)-
Names
[ CAS No. ]:
2845-82-1
[ Name ]:
1,3,4-Oxadiazol-2(3H)-one,5-(4-pyridinyl)-
[Synonym ]:
5-pyridin-4-yl-3H-[1,3,4]oxadiazol-2-one
S 57 (VAN)
5-(4-Pyridyl)-1,3,4-oxadiazol-2-ol
Neovadrine
2-Pyridyl-(4)-1,3,4-oxadiazolon-(5) [German]
1,3,4-OXADIAZOL-2-OL,5-(4-PYRIDINYL)
5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one
5-[4]Pyridyl-3H-[1,3,4]oxadiazol-2-on
5-(4-Pyridinyl)-1,3,4-oxadiazolin-2-one
5-[4]pyridyl-3H-[1,3,4]oxadiazol-2-one
S 57
Chemical & Physical Properties
[ Density]:
1.53g/cm3
[ Molecular Formula ]:
C7H5N3O2
[ Molecular Weight ]:
163.13300
[ Exact Mass ]:
163.03800
[ PSA ]:
71.78000
[ LogP ]:
0.42490
[ Index of Refraction ]:
1.702
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RO0905000
- CHEMICAL NAME :
- 1,3,4-Oxadiazol-2-ol, 5-(4-pyridinyl)-
- CAS REGISTRY NUMBER :
- 2845-82-1
- BEILSTEIN REFERENCE NO. :
- 0146642
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C7-H5-N3-O2
- MOLECULAR WEIGHT :
- 163.15
- WISWESSER LINE NOTATION :
- T6NJ D- CT5NN DOJ EQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Behavioral - euphoria
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,22,1962
Safety Information
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%