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Linoleic Acid-13C18

Names

[ CAS No. ]:
287111-25-5

[ Name ]:
Linoleic Acid-13C18

[Synonym ]:
9,12-Octadecadienoic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18-13C18 acid, (9Z,12Z)-
LINOLEIC ACID-13C18
(9Z,12Z)-(13C18)-9,12-Octadecadienoic acid
cis-9,cis-12-Octadecadienoic acid-13C18
13C Labeled linoleic acid
13C Labeled telfairic acid
9-cis,12-cis-Linoleic acid-13C18
MFCD01075561

Biological Activity

[Description]:

Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Molecular Formula ]:
13C18H32O2

[ Molecular Weight ]:
298.313

[ Exact Mass ]:
298.300629

[ Index of Refraction ]:
1.478

[ Storage condition ]:
-20°C

Related Compounds