Sodium L-pyroglutamate

Names

[ Name ]:
Sodium L-pyroglutamate

[Synonym ]:
sodium pyrrolidonecarboxylate
Sodium L-pyroglutama
Sodium (2S)-5-oxo-2-pyrrolidinecarboxylate
sodium L-pyrrolidone carboxylate
SODIUMPYROGLUTAMICACID
Sodium 5-oxo-2-pyrrolidinecarboxylate
Proline, 5-oxo-, sodium salt (1:1)
L-Proline, 5-oxo-, sodium salt (1:1)
sodium (2S)-5-oxopyrrolidine-2-carboxylate
L-PCA-NA
EINECS 249-277-1
Sodium PCA
Sodium pyroglutamate
dium L-pyroglutamate
L-PCA-Na=SodiumPCA
sodium 5-oxo-L-prolinate
SodiumL-pyroglutamate
UNII:469OTG57A2
Proline, 5-oxo-, monosodium salt
sodium salt of pyroglutamic acid
5-Oxoproline sodium salt

Biological Activity

[Description]:

Sodium L-pyroglutamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[Target]

Human Endogenous Metabolite

Chemical & Physical Properties

[ Density]:
1.45

[ Boiling Point ]:
453.1ºC at 760 mmHg

[ Melting Point ]:
125ºC

[ Molecular Formula ]:
C₅H₆NNaO₃

[ Molecular Weight ]:
151.096

[ Flash Point ]:
227.8ºC

[ Exact Mass ]:
151.024536

[ PSA ]:
69.23000

[ Vapour Pressure ]:
1.79E-09mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TW4000000

CHEMICAL NAME :: L-Proline, 5-oxo-, monosodium salt

CAS REGISTRY NUMBER :: 28874-51-3

LAST UPDATED :: 199504

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H7-N-O3.Na

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 gm/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 23,717,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 690 gm/kg/26W-C

TOXIC EFFECTS :: Cardiac - changes in heart weight Liver - changes in liver weight Related to Chronic Data - changes in testicular weight

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 23,717,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2456 No. of Facilities: 190 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 4559 (estimated) No. of Female Employees: 3989 (estimated)

Safety Information

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%