(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

Names

[ Name ]:
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

[Synonym ]:
2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (1R,3S,4S)-
(1R,3S,4S)-2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
T55 A CNTJ CVOX1&1&1 DVQ &&(1R,3S,4S)- Form

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
371.0±25.0 °C at 760 mmHg

[ Melting Point ]:
147-152ºC

[ Molecular Formula ]:
C₁₂H₁₉NO₄

[ Molecular Weight ]:
241.284

[ Flash Point ]:
178.2±23.2 °C

[ Exact Mass ]:
241.131409

[ PSA ]:
66.84000

[ LogP ]:
0.98

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.527

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H335-H360-H400

[ Precautionary Statements ]:
P201-P261-P273-P305 + P351 + P338-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi: Irritant;N: Dangerous for the environment;

[ Risk Phrases ]:
61-36/37/38

[ Safety Phrases ]:
53-26-61

[ RIDADR ]:
UN 3077 9/PG 3

Articles

Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid.

Bioorg. Med. Chem. Lett. 16 , 1628, (2006)

Prolonged hepatitis C infection is the leading cause for cirrhosis of the liver and hepatocellular carcinoma. The etiological agent HCV virus codes a single polyprotein of approximately 3000 amino aci...

Tetrahedron Lett. 36 , 6765, (1995)