USP1-IN-6

Names

[ CAS No. ]:
2925547-95-9

[ Name ]:
USP1-IN-6

Biological Activity

[Description]:

USP1-IN-6 (compound 11) is a USP1 inhibitor (IC50<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC50 <50 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[Target]

IC50: <50 nM (USP1)[1]


[References]

[1]. Wu J, et al. Preparation of heteroaromatic compounds as small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof. World Intellectual Property Organization, WO2023083285 A1. 2023-05-19.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H27F3N8O

[ Molecular Weight ]:
560.57

Related Compounds