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ACBI3

Names

[ CAS No. ]:
2938169-76-5

[ Name ]:
ACBI3

Biological Activity

[Description]:

ACBI3 (compound 7) is a pan-KRAS degrader. ACBI3 achieves in vivo degradation of oncogenic KRAS[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Chuan Zhou, et al. Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations. J Med Chem. 2022, 65, 5.  

Chemical & Physical Properties

[ Molecular Formula ]:
C50H62N14O6S2

[ Molecular Weight ]:
1019.25

Related Compounds