epolamine

Names

[ Name ]:
epolamine

[Synonym ]:
epolamine
2-Pyrrolidinoethanol
2-pyrrolidin-1-ylethanol
N-(2-Hydroxyethyl)pyrrolidine
1-Pyrrolidineethanol
2-(1-Pyrrolidinyl)ethanol
EINECS 220-976-3
2-(pyrrolidin-1-yl)ethanol
N-hydroxyethyl pyrrolidine
MFCD00003181
Pyrrolidinoethanol
1-Pyrrolinineethanol
1-(2-Hydroxyethyl)pyrrolidine

Biological Activity

[Description]:

2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
177.6±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₃NO

[ Molecular Weight ]:
115.18

[ Flash Point ]:
56.1±0.0 °C

[ Exact Mass ]:
115.099716

[ PSA ]:
23.47000

[ LogP ]:
0.49

[ Vapour Pressure ]:
0.3±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.484

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UY1175000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Diclofenac Salts, VIII. Effect of the Counterions on the Permeation through Porcine Membrane from Aqueous Saturated Solutions.

Pharmaceutics 4 , 413-29, (2013)

The following bases: monoethylamine (EtA), diethylamine (DEtA), triethylamine (TEtA), monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA), pyrrolidine (Py), piperidine (Pp), morpholine...

Effectiveness and safety of diclofenac epolamine topical patch 1.3% for the treatment of acute pain due to back strain: an open-label, uncontrolled study.

Phys. Sportsmed. 39(1) , 11-8, (2011)

The diclofenac epolamine topical patch 1.3% (DETP) is indicated for topical treatment of acute pain due to minor strains, sprains, and contusions. This exploratory, multicenter, open-label study evalu...

Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-[14C]-pyrrolidine (HEP, Epolamine) in male healthy volunteers.

Eur. J. Drug Metab. Pharmacokinet. 21(3) , 261-8, (1996)

N-(2-hydroxyethyl)-pyrrolidine (HEP, Epolamine) is a strong base used to salify organic acids of pharmaceutical interest in order to improve their solubility in water. Diclofenac-HEP (Flector) is the ...