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Taurohyodeoxycholic Acid

Names

[ CAS No. ]:
2958-04-5

[ Name ]:
Taurohyodeoxycholic Acid

[Synonym ]:
Taurohyodesoxycholsaeure
tatsinine perchlorate

Biological Activity

[Description]:

Taurohyodeoxycholic acid is the tauroconjugated form of Hyodeoxycholic acid (HDCA, a dihydroxylated natural bile acid). Taurohyodeoxycholic acid induces a biliary phospholipid secretion and suggests a hepatoprotective potential. Taurohyodeoxycholic acid also can promote gallstone dissolution[1][1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Roda A, et, al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5.

[2]. Carubbi F, et, al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. Biochim Biophys Acta. 2002 Jan 30;1580(1):31-9.

Chemical & Physical Properties

[ Density]:
1.216g/cm3

[ Molecular Formula ]:
C26H45NO6S

[ Molecular Weight ]:
499.70400

[ Exact Mass ]:
499.29700

[ PSA ]:
132.31000

[ LogP ]:
4.86900

[ Index of Refraction ]:
1.552

Related Compounds