C2-8

Names

[ Name ]:
C2-8

[Synonym ]:
N-(4-bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide
C2-8
Polyglutamine Aggregation Inhibitor III,C2-8

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₄Br₂N₂O₃S

[ Molecular Weight ]:
510.19900

[ Exact Mass ]:
507.90900

[ PSA ]:
83.65000

[ LogP ]:
6.49150

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H413

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.

Proc. Natl. Acad. Sci. U. S. A. 102 , 892-897, (2005)

Polyglutamine (polyQ) disorders, including Huntington's disease (HD), are caused by expansion of polyQ-encoding repeats within otherwise unrelated gene products. In polyQ diseases, the pathology and d...