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Fluacizine

Names

[ CAS No. ]:
30223-48-4

[ Name ]:
Fluacizine

[Synonym ]:
phtaloyl-triglycil ethyl ester
fluoracizine
phth-gly-gly-gly-OEt
Thalinil
Fluoracizin
N-[N-(N,N-Phthaloyl-glycyl)-glycyl]-glycin-aethylester
Phtalazol
Ftalazol
N-(4-thiazol-2-ylsulfamoyl-phenyl)-phthalamic acid
2-[({4-[(2-thiazolylamino)sulfonyl]phenyl}amino)carbonyl]-benzoic acid
Sulftalyl
PST
Taloudron
N-(4-Thiazol-2-ylsulfamoyl-phenyl)-phthalamidsaeure
Phthaloyl-glycyl-glycyl-glycin-ethylester
Taleudron
Ftalysept
Talidine
Phthoracizin
Cremothalidine
N-[N-(N,N-phthaloyl-glycyl)-glycyl]-glycine ethyl ester
entexidin
N-Phthaloylacetyl-glycyl-glycin-ethylester

Chemical & Physical Properties

[ Density]:
1.267g/cm3

[ Boiling Point ]:
528.6ºC at 760mmHg

[ Molecular Formula ]:
C20H21F3N2OS

[ Molecular Weight ]:
394.45400

[ Flash Point ]:
273.5ºC

[ Exact Mass ]:
394.13300

[ PSA ]:
48.85000

[ LogP ]:
5.63160

[ Index of Refraction ]:
1.569

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO4700000
CHEMICAL NAME :
Phenothiazine, 10-diethylaminopropionyl-3-trifluoromethyl-, hydrochloride
CAS REGISTRY NUMBER :
30223-48-4
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H21-F3-N2-O-S
MOLECULAR WEIGHT :
394.49
WISWESSER LINE NOTATION :
T C666 BN ISJ BV2N2&2 FXFFF &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10 mg/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 36,399,1973
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
10 mg/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 36,178,1973
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
140 mg/kg
SEX/DURATION :
female 16-29 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 36,399,1973
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
140 mg/kg
SEX/DURATION :
female 16-29 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 36,178,1973

Safety Information

[ RIDADR ]:
UN 3249

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2934300000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%