2-Nitrophenylhydrazine

Names

[ Name ]:
2-Nitrophenylhydrazine

[Synonym ]:
MFCD00007577
2-nitrophenylhydrazide
2-Nitrophenylhydrazine,moistened with ca water
o-Nitrophenythydrazine
2-nitrophenyl-hydrazine
O-NITROPHENYLHYDRAZINE
ortho-nitrophenylhydrazine
2-Nitrophenylhydrazine
(2-Nitrophenyl)hydrazine
EINECS 221-222-6
2-Nitrophenylhrdrazine

Chemical & Physical Properties

[ Melting Point ]:
91-93 °C(lit.)

[ Molecular Formula ]:
C₆H₇N₃O₂

[ Molecular Weight ]:
153.13900

[ Exact Mass ]:
153.05400

[ PSA ]:
83.87000

[ LogP ]:
2.17690

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV8210000

CHEMICAL NAME :: Hydrazine, (o-nitrophenyl)-

CAS REGISTRY NUMBER :: 3034-19-3

BEILSTEIN REFERENCE NO. :: 0512797

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H7-N3-O2

MOLECULAR WEIGHT :: 153.16

WISWESSER LINE NOTATION :: ZMR BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 178 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 7 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 173,233,1986

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H302-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
-

[ RTECS ]:
MV8210000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Liquid chromatographic determination of free and total fatty acids in milk and milk products as their 2-nitrophenylhydrazides.

J. Chromatogr. A. 523 , 235-46, (1990)

A high-performance liquid chromatographic (HPLC) method with direct derivatization is described for the determination of both free fatty acids and total fatty acids in milk and milk products. The meth...

Determination of methyl ethyl ketone in human urine after derivatization with o-nitrophenylhydrazine, using solid-phase extraction and reversed-phase high-performance liquid chromatography and ultraviolet detection.

J. Chromatogr. A. 489(2) , 419-24, (1989)

On-line determination of carboxylic acids, aldehydes and ketones by high-performance liquid chromatography-diode array detection-atmospheric pressure chemical ionisation mass spectrometry after derivatization with 2-nitrophenylhydrazine.

J. Chromatogr. A. 1031(1-2) , 35-50, (2004)

2-Nitrophenylhydrazine (2-NPH) is widely used for the derivatization of carboxylic acids, aldehydes and ketones, in industrial and biological samples. These compounds react with 2-NPH to form derivati...