5-methoxyquinolin-8-amine

Names

[ CAS No. ]:
30465-68-0

[ Name ]:
5-methoxyquinolin-8-amine

[Synonym ]:
5-methoxy-8-aminoquinoline
5-methoxy-8-quinolinamine
5-methoxyquinolin-8-ylamine
8-amino-5-methoxyquinoline

Chemical & Physical Properties

[ Density]:
1.217 g/cm3

[ Boiling Point ]:
355.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₀N₂O

[ Molecular Weight ]:
174.19900

[ Flash Point ]:
168.9ºC

[ Exact Mass ]:
174.07900

[ PSA ]:
48.14000

[ LogP ]:
2.40680

[ Index of Refraction ]:
1.664

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Access to Different Isomeric Dibenzoxazepinones through Copper-Catalyzed C-H Etherification and C-N Bond Construction with Controllable Smiles Rearrangement.

Org. Lett. 18(3) , 380-3, (2016)

An efficient new way to access two regio-isomeric dibenzoxazepinones is reported from 8-aminoquinoline benzamides and 2-bromophenols. Through choice of conditions, the reaction proceeds either through...

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated ? C(sp³)-H Bonds. He G, et al.

Angew. Chem. Weinheim Bergstr. Ger. 125(42) , 11330-11334, (2013)