Benzyl 1-piperazinecarboxylate
Names
[ CAS No. ]:
31166-44-6
[ Name ]:
Benzyl 1-piperazinecarboxylate
[Synonym ]:
Benzyl piperazine-1-carboxylate
Piperazine-1-carboxylic Acid Benzyl Ester
4-benzyloxycarbonylpiperazine
Benzyl 1-piperazinecarboxylate
1-Z-Piperazine
N-carbobenzyloxypiperazine
1-(Benzyloxycarbonyl)piperazine
1-Cbz-Piperazine
1-Piperazinecarboxylic acid, phenylmethyl ester
benzyl N-piperazinecarboxylate
MFCD00274317
phenylmethyl piperazinecarboxylate
1-Carbobenzoxypiperazine
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
352.4±30.0 °C at 760 mmHg
[ Molecular Formula ]:
C12H16N2O2
[ Molecular Weight ]:
220.27
[ Flash Point ]:
166.9±24.6 °C
[ Exact Mass ]:
220.121185
[ PSA ]:
41.57000
[ LogP ]:
1.17
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.547
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
European J. Org. Chem. 2001(15) , 2825-39, (2001)
Novel piperazines: potent melanocortin-4 receptor antagonists with anxiolytic-like activity.
Bioorg. Med. Chem. 15(6) , 2375-85, (2007)
In the present study, we found that a novel piperazine compound, 11a, showed a moderate affinity (IC(50)=333nM) for the MC4 receptor. We developed the new type of piperazine compounds and found that m...