Sudan II

Names

[ Name ]:
Sudan II

[Synonym ]:
Red B
EINECS 221-490-4
FAT RED
1-(2,4-Xylidylazo)-2-naphthol
AKA505
1-(2,4-Xylylazo)-2-naphthol,Solvent Orange 7
2,4-dimethyl-1-phenylazo-2-naphthol
redno.5
Rot B
SUDAN 2
1-(2',4'-dimethylbenzeneazo)-2-naphthol
1-[(2,4-dimethylphenyl)azo]-2-naphthalenol
m-Xylol-(4 azo 1)-naphthol-(2)
SUDAN
1,2-Naphthalenedione, 1-[2-(2,4-dimethylphenyl)hydrazone], (1Z)-
1-(2,4-Dimethyl-phenylazo)-[2]naphthol
MFCD00003896
Solvent Orange 7
(1Z)-1-[(2,4-Dimethylphenyl)hydrazono]-2(1H)-naphthalenone
Sudan II [=1-(2,4-Xylidylazo)-2-naphthol]

Biological Activity

[Description]:

Sudan Red II is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

苏丹 II 是一种染料。

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
429.6±55.0 °C at 760 mmHg

[ Melting Point ]:
156-158ºC

[ Molecular Formula ]:
C₁₈H₁₆N₂O

[ Molecular Weight ]:
276.33

[ Flash Point ]:
213.6±31.5 °C

[ Exact Mass ]:
276.126251

[ PSA ]:
44.95000

[ LogP ]:
4.56

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.616

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL5850000

CHEMICAL NAME :: 2-Naphthol, 1-(2,4-xylylazo)-

CAS REGISTRY NUMBER :: 3118-97-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C18-H16-N2-O

MOLECULAR WEIGHT :: 276.36

WISWESSER LINE NOTATION :: L66J BNUNR B1 D1& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 50 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 44,9,1977 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,233,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,233,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1408 No. of Facilities: 141 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 3517 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1408 No. of Facilities: 206 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 3262 (estimated) No. of Female Employees: 1087 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S36/37-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QL5850000

[ HS Code ]:
2927000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Development of a method for the analysis of seven banned azo-dyes in chilli and hot chilli food samples by pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry.

Talanta 78(1) , 178-86, (2009)

An automated, confirmatory and sensitive procedure has been developed and validated for the determination of Sudan (I-IV), Sudan Orange G, Sudan Red 7B and Para Red in hot chilli food samples. The pro...

Preparation of anti-Sudan red monoclonal antibody and development of an indirect competitive enzyme-linked immunosorbent assay for detection of Sudan red in chilli jam and chilli oil.

Analyst 135(10) , 2566-72, (2010)

Sudan dyes are banned to be used in food additives because of the carcinogenicity of their metabolites. A rapid and sensitive indirect competitive enzyme-linked immunosorbent assay (ELISA) was develop...