2-Trifluoromethylbenzimidazole

Names

[ CAS No. ]:
312-73-2

[ Name ]:
2-Trifluoromethylbenzimidazole

[Synonym ]:
Benzimidazole,2-trifluoromethyl
2-Trifluoromethylbenzimidazole
2-trifluoromethyl-1H-benzimidazole
2-Trifluoromethyl-1H-benzoimidazole
1H-Benzimidazole, 2-(trifluoromethyl)-
2-(Trifluoromethyl)benzimidazole
2-(Trifluoromethyl)-1H-benzimidazole
MFCD00022675

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
262.8±40.0 °C at 760 mmHg

[ Melting Point ]:
208-211 °C(lit.)

[ Molecular Formula ]:
C₈H₅F₃N₂

[ Molecular Weight ]:
186.134

[ Flash Point ]:
112.7±27.3 °C

[ Exact Mass ]:
186.040482

[ PSA ]:
28.68000

[ LogP ]:
2.40

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Water Solubility ]:
PRACTICALLY INSOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE1576000

CHEMICAL NAME :: Benzimidazole, 2-trifluoromethyl-

CAS REGISTRY NUMBER :: 312-73-2

BEILSTEIN REFERENCE NO. :: 0163420

LAST UPDATED :: 199803

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H5-F3-N2

MOLECULAR WEIGHT :: 186.15

WISWESSER LINE NOTATION :: T56 BM DNJ CXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSSCBG Pesticide Science. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1970- Volume(issue)/page/year: 15,31,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07536

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25;R36/37/38

[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
DE1576000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%