D-serine
Names
[ CAS No. ]:
312-84-5
[ Name ]:
D-serine
[Synonym ]:
Ser
S-serine
(S)-2-Amino-3-hydroxypropionic acid
(R)-2-Amino-3-hydroxypropionic acid
D-2-Amino-3-hydroxypropionic Acid
L-3-Hydroxy-2-aminopropionic acid
(S)-a-Amino-b-hydroxypropionic acid
(S)-2-amino-3-hydroxypropanoic acid
DW75
Propanoic acid, 2-amino-3-hydroxy-, (S)-
EINECS 206-229-4
H-Ser-OH
H-D-SER-OH
(S)-2-amino-3-hydroxy-Propanoic acid
2-Amino-3-hydroxypropanoic acid, (S)-
β-Hydroxyalanine
MFCD00004269
D-Serine
Serine, L-
(S)-(-)-serine
D-Serin
P1010
(R)-2-Amino-3-hydroxypropanoic acid
L-2-Amino-3-hydroxypropionic acid
(-)-Serine
L-Serine
3-hydroxy-L-Alanine
L-Ser
b-Hydroxy-L-alanine
(R)-Serine
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
394.8±32.0 °C at 760 mmHg
[ Melting Point ]:
220 °C
[ Molecular Formula ]:
C3H7NO3
[ Molecular Weight ]:
105.093
[ Flash Point ]:
192.6±25.1 °C
[ Exact Mass ]:
105.042595
[ PSA ]:
83.55000
[ LogP ]:
-1.58
[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C
[ Index of Refraction ]:
1.519
[ Water Solubility ]:
346 g/L (20 ºC)
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
VT8200000
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Oncotarget 6 , 13072-87, (2015)
The therapeutic efficacy of nucleoside analogues, e.g. gemcitabine, against cancer cells can be augmented by inhibitors of checkpoint kinases, including Wee1, ATR, and Chk1. We have compared the chemo...
Angiotensin II activates the RhoA exchange factor Arhgef1 in humans.Hypertension 65 , 1273-8, (2015)
Although a causative role for RhoA-Rho kinase has been recognized in the development of human hypertension, the molecular mechanism(s) and the RhoA guanine exchange factor(s) responsible for the overa...
Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.Oncotarget 6(6) , 4286-98, (2015)
Current knowledge indicates that the mammalian target of rapamycin (mTOR) functions as two complexes, mTORC1 and mTORC2, regulating cell growth, proliferation, survival, differentiation, and motility....