p-Cresyl sulfate

Names

[ Name ]:
p-Cresyl sulfate

[Synonym ]:
sulfuric acid mono-p-tolyl ester
p-cresol sulfate
Schwefelsaeure-mono-p-tolylester
Schwefelsaeure-mono-(4-methyl-phenylester)
p-Tolyl-hydrogensulfat
4-cresol sulfate
p-Cresyl Sulfate
Sulfuric acid,mono(4-methylphenyl) ester

Biological Activity

[Description]:

p-Cresyl Sulfate, a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver, existed in the blood of patients with chronic kidney disease (CKD).

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

Microbial Metabolite

[References]

[1]. Peng YS, Syu JP, Wang SD, Pan PC, Kung HN. BSA-bounded p-cresyl sulfate potentiates the malignancy of bladder carcinoma by triggering cell migration and EMT through the ROS/Src/FAK signaling pathway. Cell Biol Toxicol. 2020;36(4):287-300.

[2]. Gryp T, Vanholder R, Vaneechoutte M, Glorieux G. p-Cresyl Sulfate. Toxins (Basel). 2017;9(2):52. Published 2017 Jan 29.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₈O₄S

[ Molecular Weight ]:
188.20100

[ Exact Mass ]:
188.01400

[ PSA ]:
71.98000

[ LogP ]:
2.25740

Safety Information

[ HS Code ]:
2902909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%