2-(Cyclohexanecarboxamido)acetic acid

Names

[ Name ]:
2-(Cyclohexanecarboxamido)acetic acid

[Synonym ]:
Cyclohexanoylglycine
Hexahydrohippurate
cyclohexanecarbonylglycine
N-cyclohexanoyl glycine
cyclohexylcarbonylglycine

Biological Activity

[Description]:

Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Uenishi H, Bacteriostatic or antibacterial agents containing amide of cyclohexanecarboxylic acid with amino acid and phytopathogenic bacteria control agents, food, etc., containing the agents: Japan, JP2015093867[P]. 2015-05-18.

[2]. Brewster D, et al. The metabolism of cyclohexanecarboxylate in the rat. Biochem J. 1977 Jun 15;164(3):595-600.

Chemical & Physical Properties

[ Density]:
1.174g/cm3

[ Boiling Point ]:
434.6ºC at 760mmHg

[ Molecular Formula ]:
C₉H₁₅NO₃

[ Molecular Weight ]:
185.22000

[ Flash Point ]:
216.6ºC

[ Exact Mass ]:
185.10500

[ PSA ]:
66.40000

[ LogP ]:
1.15840

[ Index of Refraction ]:
1.503

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%