4'-Fluoro-4-biphenylamine
Names
[ CAS No. ]:
324-93-6
[ Name ]:
4'-Fluoro-4-biphenylamine
[Synonym ]:
4'-Fluoro-4-aminobiphenyl
4-Amino-4'-fluorobiphenyl
[1,1'-Biphenyl]-4-amine, 4'-fluoro-
4'-Fluorobiphenyl-4-amine
4'-Fluoro-4-aminodiphenyl
4'-Fluoro-biphenyl-4-amine
4-Amino-4'-fluorodiphenyl
EINECS 206-306-2
4'-Fluoro-biphenyl-4-ylamine
4'-Fluoro-4-biphenylamine
MFCD00025338
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
306.6±17.0 °C at 760 mmHg
[ Melting Point ]:
119-121ºC
[ Molecular Formula ]:
C12H10FN
[ Molecular Weight ]:
187.213
[ Flash Point ]:
156.9±7.5 °C
[ Exact Mass ]:
187.079727
[ PSA ]:
26.02000
[ LogP ]:
2.70
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.599
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DU9625000
- CHEMICAL NAME :
- 4-Biphenylamine, 4'-fluoro-
- CAS REGISTRY NUMBER :
- 324-93-6
- BEILSTEIN REFERENCE NO. :
- 2936239
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C12-H10-F-N
- MOLECULAR WEIGHT :
- 187.23
- WISWESSER LINE NOTATION :
- ZR DR DF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 520 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2000 mg/kg/W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1990 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Embryo
- DOSE/DURATION :
- 500 ug/L
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 52,1167,1974
Safety Information
[ Hazard Codes ]:
T
[ Risk Phrases ]:
23/24/25-33
[ Safety Phrases ]:
24/25-36/37/39-39-26
[ HS Code ]:
2921499090
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%