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aspon (tm)

Names

[ CAS No. ]:
3244-90-4

[ Name ]:
aspon (tm)

[Synonym ]:
O,O,O',O'-tetrapropyl pyrophosphorothioate
A 42
ASPON
EINECS 221-817-0
1,2-Dithio-diphosphorsaeure-tetra-O-propylester
Tetra-n-propyl dithionopyrophosphate
Tetra-O-propyl-1,2-dithio-phosphat
Tetra-n-propyl dithiopyrophosphate
Caswell No. 845A
1,2-dithio-diphosphoric acid tetra-O-propyl ester
ENT 16,894
Tetrapropyl thiodiphosphate
Propyl thiopyrophosphate
Stauffer asp-51
ASP 51

Chemical & Physical Properties

[ Density]:
1.173g/cm3

[ Boiling Point ]:
381.6ºC at 760mmHg

[ Melting Point ]:
-44.9°C

[ Molecular Formula ]:
C12H28O5P2S2

[ Molecular Weight ]:
378.42500

[ Flash Point ]:
184.6ºC

[ Exact Mass ]:
378.08500

[ PSA ]:
129.95000

[ LogP ]:
6.45960

[ Appearance of Characters ]:
liquid

[ Index of Refraction ]:
1.498

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XN4550000
CHEMICAL NAME :
Thiopyrophosphoric acid, tetrapropyl ester
CAS REGISTRY NUMBER :
3244-90-4
BEILSTEIN REFERENCE NO. :
1715467
LAST UPDATED :
199612
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C12-H28-O5-P2-S2
MOLECULAR WEIGHT :
378.46
WISWESSER LINE NOTATION :
3OPS&O3&OPS&O3&O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,88,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 8,350,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,379,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CJCHAG Canadian Journal of Chemistry. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.29- 1951- Volume(issue)/page/year: 34,1819,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CJCHAG Canadian Journal of Chemistry. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.29- 1951- Volume(issue)/page/year: 34,1819,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4410 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CJCHAG Canadian Journal of Chemistry. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.29- 1951- Volume(issue)/page/year: 34,1819,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3830 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 1,42,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
436 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,147,1964 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
21/22-50/53

[ Safety Phrases ]:
S60;S61;S36/S37

[ RIDADR ]:
UN 3018

[ RTECS ]:
XN4550000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Precursor & DownStream


Related Compounds