6-(2-amino-1,6-dimethyl-pyrimidin-4-ylidene)amino-1,2-dimethyl-quinolin-4-amine
Names
[ CAS No. ]:
3270-78-8
[ Name ]:
6-(2-amino-1,6-dimethyl-pyrimidin-4-ylidene)amino-1,2-dimethyl-quinolin-4-amine
[Synonym ]:
quinapyraminemethylsulfate
QUINAPYRAMINE SULFATE
antrycidemethylsulfate
antrycide
Chemical & Physical Properties
[ Molecular Formula ]:
C19H28N6O8S2
[ Molecular Weight ]:
532.59100
[ Exact Mass ]:
532.14100
[ PSA ]:
234.34000
[ LogP ]:
2.99160
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA0345000
- CHEMICAL NAME :
- Quinaldinium, 4-amino-6-((2-amino-1,6-dimethylpyrimidinium-4-yl)ami no)-1-methyl-, bis(methyl sulfate)
- CAS REGISTRY NUMBER :
- 3270-78-8
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H21-N6.C-H4-O4-S.C-H3-O4-S
- MOLECULAR WEIGHT :
- 532.65
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,112,1985