Methyl dichlorophosphite

Names

[ Name ]:
Methyl dichlorophosphite

[Synonym ]:
O-methyl phosphodichlorite
O-methyl phosphorodichloridite
methyl phosphodichloridite
Methyl dichlorophosphite
Methyl phosphorodichloridoite
Phosphorodichloridous acid, methyl ester
Methoxydichlorophosphine
EINECS 221-915-3
Dichloro Methyl Phosphite
MFCD00000524
methyl phosphorodichloridite
Dichloromethoxyphosphine

Chemical & Physical Properties

[ Density]:
1.376 g/mL at 20 °C(lit.)

[ Boiling Point ]:
89.4±9.0 °C at 760 mmHg

[ Melting Point ]:
−91 °C(lit.)

[ Molecular Formula ]:
CH₃Cl₂OP

[ Molecular Weight ]:
132.914

[ Flash Point ]:
7.9±18.7 °C

[ Exact Mass ]:
131.929855

[ PSA ]:
22.82000

[ LogP ]:
3.29

[ Vapour Pressure ]:
66.3±0.2 mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.474(lit.)

[ Storage condition ]:
−20°C

[ Stability ]:
Flammable.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H314-H335

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2920 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2909199090

Customs

[ HS Code ]: 2909199090

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Radical deoxygenation of hydroxyl groups via phosphites.

J. Am. Chem. Soc. 126(41) , 13190-1, (2004)

A highly efficient, two-step sequence method for the deoxygenation of hydroxyl groups has been developed. The method involves the preparation of the 2-(2-iodophenyl)ethyl methyl phosphite derivative o...

Facile synthesis of phosphonamidate- and phosphonate-linked phosphonopeptides.

J. Pept. Sci. 12(4) , 303-9, (2006)

A direct method for the preparation of phosphonamidate- and phosphonate-linked phosphonopeptides has been developed. Using this method, both phosphonopeptides were prepared in acceptable yields direct...

Syringe method for stepwise chemical synthesis of oligonucleotides.

Nucleic Acids Res. 10(10) , 3249-60, (1982)

A simple procedure is described for synthesis of oligonucleotides by phosphate chemistry. Chains can be constructed rapidly with minimal equipment (a syringe and reagent bottles). The method is illust...