4-(Trifluoromethyl)phenylacetic acid

Names

[ Name ]:
4-(Trifluoromethyl)phenylacetic acid

[Synonym ]:
2-[4-(Trifluoromethyl)phenyl]acetic acid
Benzeneacetic acid, 4-(trifluoromethyl)-
(alpha,alpha,alpha-Trifluoro-p-tolyl)acetic acid
(α,α,α-Trifluoro-p-tolyl)acetic acid
EINECS 251-263-5
[4-(Trifluoromethyl)phenyl]acetic acid
2-(4-(Trifluoromethyl)phenyl)acetic acid
QV1R DXFFF
MFCD00004352
4-(Trifluoromethyl)benzeneacetic acid
4-trifluorometylphenylacetic acid
4-(Trifluoromethyl)phenylacetic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
263.1±35.0 °C at 760 mmHg

[ Melting Point ]:
82-85 °C(lit.)

[ Molecular Formula ]:
C₉H₇F₃O₂

[ Molecular Weight ]:
204.146

[ Flash Point ]:
112.9±25.9 °C

[ Exact Mass ]:
204.039810

[ PSA ]:
37.30000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.475

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Constructing multiply substituted arenes using sequential palladium(II)-catalyzed C-H olefination.

Angew. Chem. Int. Ed. Engl. 49(35) , 6169-73, (2010)