trans-1-methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone
Names
[ CAS No. ]:
33224-01-0
[ Name ]:
trans-1-methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone
[Synonym ]:
trans-4'-Carboxycotinine
1-methyl-5-oxo-2-pyridin-3-yl-pyrrolidine-3-carboxylic acid
MFCD00075394
trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone
CARBOXY COTININE
Chemical & Physical Properties
[ Density]:
1.327g/cm3
[ Boiling Point ]:
483.8ºC at 760mmHg
[ Melting Point ]:
194-195 °C(lit.)
[ Molecular Formula ]:
C11H12N2O3
[ Molecular Weight ]:
220.22500
[ Flash Point ]:
246.4ºC
[ Exact Mass ]:
220.08500
[ PSA ]:
70.50000
[ LogP ]:
0.62350
[ Index of Refraction ]:
1.583
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Exp. Mol. Med. 45 , e43, (2013)
We present a bispecific antibody that recognizes an antigen and a hapten and can be applied to various biological assays, including immunoblotting and immunoprecipitation. In immunoblot analysis of se...
Bispecific Her2 × cotinine antibody in combination with cotinine-(histidine)2-iodine for the pre-targeting of Her2-positive breast cancer xenografts.J. Cancer Res. Clin. Oncol. 140(2) , 227-33, (2014)
Cotinine has optimal characteristics as a hapten for pre-targeted radioimmunotherapy (PRIT). This study was performed to evaluate the applicability of cotinine/anti-cotinine antibody to PRIT.We develo...
The use of trans-4-cotininecarboxylate to construct a polymeric copper (II) azido complex: Hydro (solvo) thermal synthesis, structure and magnetic properties. Luo F, et al.Inorganica Chim. Acta 363(14) , 4117-22, (2010)