6-chloro-[1,3]dioxolo[4,5-g]quinoline-7-carbaldehyde

Names

[ Name ]:
6-chloro-[1,3]dioxolo[4,5-g]quinoline-7-carbaldehyde

[Synonym ]:
6-chloro-2H-1,3-dioxoleno[4,5-g]quinoline-7-carbaldehyde
6-Chloro[1,3]dioxolo[4,5-g]quinoline-7-carboxaldehyde
6-chloro[1,3]dioxolo[4,5-g]quinoline-7-carbaldehyde
2-Chloro-6,7-methylenedioxy-3-quinolinecarboxaldehyde

Chemical & Physical Properties

[ Density]:
1.554g/cm3

[ Boiling Point ]:
409.3ºC at 760 mmHg

[ Melting Point ]:
230-234ºC

[ Molecular Formula ]:
C₁₁H₆ClNO₃

[ Molecular Weight ]:
235.62300

[ Flash Point ]:
201.3ºC

[ Exact Mass ]:
235.00400

[ PSA ]:
48.42000

[ LogP ]:
2.42940

[ Index of Refraction ]:
1.722

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and biological evaluation of 10,11-methylenedioxy-14-azacamptothecin.

Org. Lett. 8 , 3513, (2006)

[reaction: see text] 10,11-Methylenedioxy-14-azacamptothecin, a potent analogue of the antitumor agent camptothecin (CPT), has been prepared via a key condensation between AB and DE ring precursors. T...