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5-Methyl-3-phenyl-1H-pyrazole

Names

[ CAS No. ]:
3347-62-4

[ Name ]:
5-Methyl-3-phenyl-1H-pyrazole

[Synonym ]:
Femerazol
3-METHYL-5-PHENYLPYRAZOLE
EINECS 222-099-1
1H-Pyrazole, 5-methyl-3-phenyl-
3-methyl-5-phenyl-1h-pyrazol
5-Methyl-3-phenylpyrazole
Phemerazole
1H-Pyrazole,3-methyl-5-phenyl
MFCD00022385
5-Methyl-3-phenyl-1H-pyrazole
Pyrazole,3-methyl-5-phenyl

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
333.9±11.0 °C at 760 mmHg

[ Melting Point ]:
126-127°C

[ Molecular Formula ]:
C10H10N2

[ Molecular Weight ]:
158.200

[ Flash Point ]:
156.2±12.2 °C

[ Exact Mass ]:
158.084396

[ PSA ]:
28.68000

[ LogP ]:
2.68

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.591

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ7525000
CHEMICAL NAME :
1H-Pyrazole,3-methyl-5-phenyl-
CAS REGISTRY NUMBER :
3347-62-4
BEILSTEIN REFERENCE NO. :
0004208
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H10-N2
MOLECULAR WEIGHT :
158.22
WISWESSER LINE NOTATION :
T5MNJ C1 ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 123,200,1958
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 123,200,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - somnolence (general depressed activity)
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 123,200,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
388 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,27,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 123,200,1958

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ RTECS ]:
UQ7525000

[ HS Code ]:
2933199090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds