6-Methyl-1H-indole

Names

[ Name ]:
6-Methyl-1H-indole

[Synonym ]:
6-Methyl-1H-indole
6-Methyl indole
Indole,6-methyl
6-Me-indole
MFCD00005682
6-Methylindole
Indole, 6-methyl-
6-Metlylindole
1H-Indole,6-methyl
1H-Indole, 6-methyl-

Biological Activity

[Description]:

6-Methyl-1H-indole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

它是用于制备色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚作为潜在抗癌免疫调节剂的反应物，用于制备吲哚连接的三唑衍生物作为抗真菌剂的反应物，用于制备 N-β-D-木糖基-吲哚衍生物作为 SGLT2 抑制剂的反应物糖尿病高血糖的管理，用于制备芳基磺酰基吲哚的氨基胍衍生物作为抗真菌剂的反应物，用于制备吲哚基吲唑和吲哚基吡唑并吡啶作为白介素 2 诱导型 T 细胞激酶抑制剂的反应物，用于制备芳基磺酰乙酰基吲哚作为抗 HIV-1 药物的反应物。6-Methylindole 用于合成 benz[c,d]indol-3(1H)-one 衍生物。

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
260.3±9.0 °C at 760 mmHg

[ Melting Point ]:
29-32°C

[ Molecular Formula ]:
C₉H₉N

[ Molecular Weight ]:
131.17

[ Flash Point ]:
109.6±11.3 °C

[ Exact Mass ]:
131.073502

[ PSA ]:
15.79000

[ LogP ]:
2.60

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.655

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3334 9

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Total synthesis of 0231B, an inhibitor of 3alpha-hydroxysteroid dehydrogenase produced by Streptomyces sp. HKI0231.

Biosci. Biotechnol. Biochem. 67(3) , 659-62, (2003)

The new inhibitors of 3alpha-hydroxysteroid dehydrogenase, 0231A 1 and 0231B 2, have a unique benz[c,d]indol-3(1H)-one structure in their molecules. In our advanced studies on indole chemistry, we hav...