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Hexasodium phytate

Names

[ CAS No. ]:
34367-89-0

[ Name ]:
Hexasodium phytate

[Synonym ]:
1,2,3,4,5,6-Cyclohexanehexol, hexakis(dihydrogen phosphate), sodium salt, (1α,2α,3α,4β,5α,6β)- (1:6)
Hexasodium (1R,2S,3r,4R,5S,6s)-1,2,3,4,5,6-cyclohexanehexayl hexakis[hydrogen (phosphate)]

Biological Activity

[Description]:

Hexasodium phytate (Phytic acid hexasodium) is a phosphorus storage compound of seeds and cereal grains. Hexasodium phytate has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Hexasodium phytate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[References]

[1]. Perelló J, et al. SNF472, a novel inhibitor of vascular calcification, could be administered during hemodialysis to attain potentially therapeutic phytate levels. J Nephrol. 2018 Apr;31(2):287-296.

[2]. Zabirnyk A,et al. SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification. Vascul Pharmacol. 2019 Nov-Dec;122-123:106583.

Chemical & Physical Properties

[ Molecular Formula ]:
C6H12Na6O24P6

[ Molecular Weight ]:
791.93

[ Exact Mass ]:
791.753052

Related Compounds