3-[[1-[3-(Trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]-1-propanol
Names
[ CAS No. ]:
34580-73-9
[ Name ]:
3-[[1-[3-(Trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]-1-propanol
[Synonym ]:
itf 1027
Chemical & Physical Properties
[ Density]:
1.38g/cm3
[ Boiling Point ]:
405.4ºC at 760 mmHg
[ Molecular Formula ]:
C16H14F3N3O2
[ Molecular Weight ]:
337.29600
[ Flash Point ]:
199ºC
[ Exact Mass ]:
337.10400
[ PSA ]:
60.17000
[ LogP ]:
3.20050
[ Index of Refraction ]:
1.582
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC0210000
- CHEMICAL NAME :
- Propanol, 3-((1-(alpha,alpha,alpha-trifluoro-m-tolyl)-1H-pyrazo lo(3,4-b)pyridin-3-yl )oxy)-
- CAS REGISTRY NUMBER :
- 34580-73-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C16-H14-F3-N3-O2
- MOLECULAR WEIGHT :
- 337.33
- WISWESSER LINE NOTATION :
- T56 BNN INJ BR CXFFF& DO3Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 550 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%