4-Chloro-7-trifluoromethylquinoline
Names
[ CAS No. ]:
346-55-4
[ Name ]:
4-Chloro-7-trifluoromethylquinoline
[Synonym ]:
4-Chlor-7-trifluormethyl-chinolin
4-Chloro-7-(trifluoromethyl)quinoline
4-chloro-7-trifluoroquinoline
4-Chloro-7-trifluoromethylquinoline
EINECS 206-471-0
7-trifluoromethyl-4-chloroquinoline
Quinoline, 4-chloro-7-(trifluoromethyl)-
MFCD00006775
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
265.5±35.0 °C at 760 mmHg
[ Melting Point ]:
69-71 °C(lit.)
[ Molecular Formula ]:
C10H5ClF3N
[ Molecular Weight ]:
231.602
[ Flash Point ]:
114.4±25.9 °C
[ Exact Mass ]:
231.006256
[ PSA ]:
12.89000
[ LogP ]:
3.71
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.555
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933499090
Synthetic Route
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Acta. Pharm. 64(3) , 285-97, (2014)
Novel nineteen compounds based on a 4-aminoquinoline scaffold were designed and synthesized as potential antiproliferative agents. The new compounds were N-substituted at the 4-position by aryl or het...
Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates.J. Med. Chem. 22(5) , 554-9, (1979)
A series of (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates has been prepared and screened for analgesic and antiinflammatory properties in mice and rats. The tabulat...