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4-Chloro-7-trifluoromethylquinoline

Names

[ CAS No. ]:
346-55-4

[ Name ]:
4-Chloro-7-trifluoromethylquinoline

[Synonym ]:
4-Chlor-7-trifluormethyl-chinolin
4-Chloro-7-(trifluoromethyl)quinoline
4-chloro-7-trifluoroquinoline
4-Chloro-7-trifluoromethylquinoline
EINECS 206-471-0
7-trifluoromethyl-4-chloroquinoline
Quinoline, 4-chloro-7-(trifluoromethyl)-
MFCD00006775

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
265.5±35.0 °C at 760 mmHg

[ Melting Point ]:
69-71 °C(lit.)

[ Molecular Formula ]:
C10H5ClF3N

[ Molecular Weight ]:
231.602

[ Flash Point ]:
114.4±25.9 °C

[ Exact Mass ]:
231.006256

[ PSA ]:
12.89000

[ LogP ]:
3.71

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.555

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933499090

Synthetic Route

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Design, synthesis and potential anti-proliferative activity of some novel 4-aminoquinoline derivatives.

Acta. Pharm. 64(3) , 285-97, (2014)

Novel nineteen compounds based on a 4-aminoquinoline scaffold were designed and synthesized as potential antiproliferative agents. The new compounds were N-substituted at the 4-position by aryl or het...

Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates.

J. Med. Chem. 22(5) , 554-9, (1979)

A series of (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates has been prepared and screened for analgesic and antiinflammatory properties in mice and rats. The tabulat...


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Related Compounds