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L-Ornithine-d6 Hydrochloride

Names

[ CAS No. ]:
347841-40-1

[ Name ]:
L-Ornithine-d6 Hydrochloride

[Synonym ]:
(2S)-2,5-diamino-3,3,4,4,5,5-hexadeuteriopentanoic acid,hydrochloride

Biological Activity

[Description]:

L-Ornithine-d6 hydrochloride is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C5H7D6ClN2O2

[ Molecular Weight ]:
174.65900

[ Exact Mass ]:
174.10400

[ PSA ]:
89.34000

[ LogP ]:
1.33980


Related Compounds