poly(estradiol phosphate)
Names
[ CAS No. ]:
34828-67-6
[ Name ]:
poly(estradiol phosphate)
Chemical & Physical Properties
[ Density]:
1.37g/cm3
[ Boiling Point ]:
561.9ºC at 760 mmHg
[ Molecular Formula ]:
C18H25O5P
[ Molecular Weight ]:
352.36200
[ Flash Point ]:
293.6ºC
[ Exact Mass ]:
352.14400
[ PSA ]:
96.80000
[ LogP ]:
3.72620
[ Index of Refraction ]:
1.612
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7400000
- CHEMICAL NAME :
- 17-beta-Estra 1,3,5(10)-triene-3,17-diol, 17-dihydrogen phosphate, homopolymer
- CAS REGISTRY NUMBER :
- 34828-67-6
- LAST UPDATED :
- 199509
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg/60D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia Musculoskeletal - tumors
- REFERENCE :
- ATHBA3 Acta Radiologica: Therapy, Physics, Biology. (Stockholm, Sweden) V.1-16, 1963-77. Volume(issue)/page/year: 12,209,1973 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 41 mg/kg
- SEX/DURATION :
- male 35 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- ASUPAZ Acta Societatis Medicorum Upsaliensis. (Uppsala, Sweden) V.55-76, 1950-71. For publisher information, see UJMSAP. Volume(issue)/page/year: 73,199,1968