3-(4-methylphenyl)-1,2,35-oxadiazol-5-ol
Names
[ CAS No. ]:
3483-19-0
[ Name ]:
3-(4-methylphenyl)-1,2,35-oxadiazol-5-ol
[Synonym ]:
Sydnone,3-p-tolyl
3-p-tolyl-sydnone
N-tolyl-sydnone
Chemical & Physical Properties
[ Molecular Formula ]:
C9H8N2O2
[ Molecular Weight ]:
176.17200
[ Exact Mass ]:
176.05900
[ PSA ]:
52.97000
[ LogP ]:
1.40350
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WU7694500
- CHEMICAL NAME :
- Sydrone, 3-p-tolyl-
- CAS REGISTRY NUMBER :
- 3483-19-0
- BEILSTEIN REFERENCE NO. :
- 3672154
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H8-N2-O2
- MOLECULAR WEIGHT :
- 176.19
- WISWESSER LINE NOTATION :
- T5NNOVJ AR D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 753 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - anticonvulsant Behavioral - altered sleep time (including change in righting reflex)
- REFERENCE :
- ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 14,369,1965