3-Methoxy-5-(trifluoromethyl)aniline
Names
[ CAS No. ]:
349-55-3
[ Name ]:
3-Methoxy-5-(trifluoromethyl)aniline
[Synonym ]:
5-Methoxy-α,α,α-trifluoro-m-toluidine
3-trifluoromethyl-5-methoxyaniline
FXFFR CZ EO1
1-Amino-3-methoxy-5-(trifluoromethyl)benzene
3-Methoxy-5-(trifluoromethyl)aniline
Benzenamine, 3-methoxy-5-(trifluoromethyl)-
3-Amino-5-methoxybenzotrifluoride
5-(Trifluoromethyl)-m-anisidine
3-methyloxy-5-trifluoromethylaniline
MFCD00000393
EINECS 206-487-8
3-Methoxy-5-(trifluoromethyl)benzenamine
3-methoxy-5-trifluoromethylaniline
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
242.0±40.0 °C at 760 mmHg
[ Melting Point ]:
50-52 °C(lit.)
[ Molecular Formula ]:
C8H8F3NO
[ Molecular Weight ]:
191.150
[ Flash Point ]:
100.2±27.3 °C
[ Exact Mass ]:
191.055801
[ PSA ]:
35.25000
[ LogP ]:
2.78
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.477
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
PG3
[ WGK Germany ]:
3
[ HS Code ]:
2922299090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 18(23) , 6231-5, (2008)
A series of SYK inhibitors based on the phenylamino pyrimidine thiazole lead 4 were prepared and evaluated for biological activity. Lead optimization provided compounds with nanomolar K(i)'s against S...