Tert-butyl (triphenylphosphoranylidene)acetate

Names

[ Name ]:
Tert-butyl (triphenylphosphoranylidene)acetate

[Synonym ]:
2-Methyl-2-propanyl (triphenylphosphoranylidene)acetate
tert-Butyl 2-(triphenylphosphoranylidene)acetate
1,1-Dimethylethyl 2-(triphenylphosphoranylidene)acetate
Triphenylphoranylidene
(tert-Butoxycarbonylmethylene)triphenylphosphorane
tert-Butyl (triphenyl-λ5-phosphanylidene)acetate
EINECS 412-880-7
Acetic acid, 2-(triphenylphosphoranylidene)-, 1,1-dimethylethyl ester
1X1&1&OV1UPR&R&R
MFCD00075545
Tert-butyl (triphenylphosphoranylidene)acetate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
503.5±33.0 °C at 760 mmHg

[ Melting Point ]:
152-155 °C(lit.)

[ Molecular Formula ]:
C₂₄H₂₅O₂P

[ Molecular Weight ]:
376.428

[ Flash Point ]:
271.4±45.7 °C

[ Exact Mass ]:
376.159210

[ PSA ]:
36.11000

[ LogP ]:
4.91

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H317-H319-H373-H411

[ Precautionary Statements ]:
P273-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R25;R36;R43;R48/22;R51/53

[ Safety Phrases ]:
S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 3464 6.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

Articles

ELEMENTAL SELENIUM GENERATED BY THE PHOTOBLEACHING OF SELENOMEROCYANINE PHOTOSENSITIZERS FORMS CONJUGATES WITH SERUM MACROMOLECULES THAT ARE TOXIC TO TUMOR CELLS.

Phosphorus. Sulfur. Silicon Relat. Elem. 67 , 311, (1992)

Elemental selenium generated by the photobleaching of selenomerocyanine dyes forms conjugates with serum albumin and serum lipoproteins that are toxic to leukemia and selected solid tumor cells but we...

Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo.

J. Med. Chem. 47 , 3615-3628, (2004)

The Group IVA cytosolic phospholipase A(2) (GIVA PLA(2)) is a particularly attractive target for drug development because it is the rate-limiting provider of proinflammatory mediators. We previously r...

Orally active aldose reductase inhibitors: indazoleacetic, oxopyridazineacetic, and oxopyridopyridazineacetic acid derivatives.

J. Med. Chem. 35 , 2155, (1992)

Benzothiazole side chains featured in zopolrestat (1a) and its congeners were incorporated into oxophthalazineacetic acid replacements, including indazole, pyridazinone, and pyridopyridazinone with a ...