BENZENE, 4-ETHYNYL-1-FLUORO-2-METHYL-

Names

[ CAS No. ]:
351002-93-2

[ Name ]:
BENZENE, 4-ETHYNYL-1-FLUORO-2-METHYL-

[Synonym ]:
4-ethynyl-1-fluoro-2-methyl-Benzene
4-Fluoro-3-methylphenylacetylene
MFCD06200682

Chemical & Physical Properties

[ Density]:
1.007 g/mL at 25ºC(lit.)

[ Boiling Point ]:
169-170ºC(lit.)

[ Molecular Formula ]:
C₉H₇F

[ Molecular Weight ]:
134.15000

[ Flash Point ]:
100 °F

[ Exact Mass ]:
134.05300

[ LogP ]:
2.11540

[ Index of Refraction ]:
n20/D 1.5210(lit.)

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
10-41

[ Safety Phrases ]:
26-39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2903999090

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.

J. Med. Chem. 57(8) , 3522-31, (2014)

Carbonic anhydrase IX (CA IX) is a target for hypoxic cancer therapies, and the discovery of CA IX selective ligands is imperative for the development of these agents. Primary sulfonamides are broad s...