GELSEMINE HYDROCHLORIDE
Names
[ CAS No. ]:
35306-33-3
[ Name ]:
GELSEMINE HYDROCHLORIDE
[Synonym ]:
Gelsemine,hydrochloride
Gelsemin,Hydrochlorid
Gelsemine,monohydrochloride
EINECS 252-504-7
Gelsemine HCl
Chemical & Physical Properties
[ Boiling Point ]:
493.4ºC at 760mmHg
[ Melting Point ]:
>300ºC
[ Molecular Formula ]:
C20H23ClN2O2
[ Molecular Weight ]:
358.86200
[ Flash Point ]:
252.2ºC
[ Exact Mass ]:
358.14500
[ PSA ]:
41.57000
[ LogP ]:
2.90550
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LX9150000
- CHEMICAL NAME :
- Gelsemine, monohydrochloride
- CAS REGISTRY NUMBER :
- 35306-33-3
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H22-N2-O2.Cl-H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 500 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
- REFERENCE :
- ZEBLA3 Zeitschrift fuer Biologie. (Munich, Fed. Rep. Ger.) V.1-116, 1865-1971. Discontinued. Volume(issue)/page/year: 99,446,1939