2,3-DIHEXADECANOYL-SN-GLYCERO-1-PHOSPHOCHOLINE

Names

[ Name ]:
2,3-DIHEXADECANOYL-SN-GLYCERO-1-PHOSPHOCHOLINE

[Synonym ]:
(2S)-2,3-Bis(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosph ate
1-sn-Phosphatidylcholine

Biological Activity

[Description]:

2,3-Dipalmitoyl-sn-glycerol-1-phosphocholine is a major component of pulmonary surfactant, a monolayer that reduces lung surface tension and prevents lung collapse during exhalation.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₀H₈₀NO₈P

[ Molecular Weight ]:
734.03900

[ Exact Mass ]:
733.56200

[ PSA ]:
121.00000

[ LogP ]:
11.68200

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Unusual triskelion patterns and dye-labelled GUVs: consequences of the interaction of cholesterol-containing linear-hyperbranched block copolymers with phospholipids.

Soft Matter 11 , 6106-17, (2015)

Cholesterol (Ch) linked to a linear-hyperbranched block copolymer composed of poly(ethylene glycol) (PEG) and poly(glycerol) (hbPG) was investigated for its membrane anchoring properties. Two polyethe...

Pulmonary surfactant: functions and molecular composition.

Biochim. Biophys. Acta 1408 , 79-89, (1998)

This review briefly notes recent findings important for understanding the surface mechanical functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are discussed, w...