S-[N-BENZYL(THIOCARBAMOYL)]-L-CYSTEINE

Names

[ Name ]:
S-[N-BENZYL(THIOCARBAMOYL)]-L-CYSTEINE

[Synonym ]:
Uraton
S-[(benzylamino)carbonothioyl]cysteine
S-<N-benzyl(thiocarbamoyl)>-L-cysteine
Benzylisothiocyanate cysteine conjugate
S-(N-Benzylthiocarbamoyl)cysteine
L-Cysteine (Phenylmethyl)carbamodithioate

Chemical & Physical Properties

[ Density]:
1.363 g/cm3

[ Boiling Point ]:
459.8ºC at 760 mmHg

[ Melting Point ]:
191-193ºC

[ Molecular Formula ]:
C₁₁H₁₄N₂O₂S₂

[ Molecular Weight ]:
270.37100

[ Flash Point ]:
231.9ºC

[ Exact Mass ]:
270.05000

[ PSA ]:
132.74000

[ LogP ]:
2.29740

[ Index of Refraction ]:
1.665

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Phenylalkyl isothiocyanate-cysteine conjugates as glutathione S-transferase stimulating agents.

J. Med. Chem. 35 , 185, (1992)

To develop analogues of phenylalkyl isothiocyanate with less toxicity and better biological activity, two water-soluble phenylalkyl isothiocyanate-cysteine conjugates, S-[N-benzyl(thiocarbamoyl)]-L-cy...

The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits.

Xenobiotica 12(9) , 535-42, (1982)

1. Following oral administration of benzyl isothiocyanate or its cysteine conjugate the major metabolite isolated from urine of guinea-pigs and rabbits was a cyclic mercaptopyruvate conjugate, 4-hydro...