moxastine
Names
[ CAS No. ]:
3572-74-5
[ Name ]:
moxastine
[Synonym ]:
Spofa 325
Theadrylettae
Mephenhydramine
Mephenhydraminum
Moxastine
Therdryl
Moxastin
Chemical & Physical Properties
[ Density]:
1.013g/cm3
[ Boiling Point ]:
357.5ºC at 760mmHg
[ Molecular Formula ]:
C18H23NO
[ Molecular Weight ]:
269.38100
[ Flash Point ]:
105.5ºC
[ Exact Mass ]:
269.17800
[ PSA ]:
12.47000
[ LogP ]:
3.52830
[ Index of Refraction ]:
1.542
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KR6715000
- CHEMICAL NAME :
- Ethylamine, 2-(1,1-diphenylethoxy)-N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 3572-74-5
- BEILSTEIN REFERENCE NO. :
- 1981628
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H23-N-O
- MOLECULAR WEIGHT :
- 269.42
- WISWESSER LINE NOTATION :
- 1XR&R&O2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,323,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 110 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/kg/6W-I
- TOXIC EFFECTS :
- Liver - fatty liver degeneration
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,531,1961
Safety Information
[ HS Code ]:
2922199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%