GLYCODEOXYCHOLIC ACID
Names
[ CAS No. ]:
360-65-6
[ Name ]:
GLYCODEOXYCHOLIC ACID
[Synonym ]:
Glycodeoxycholic acid monohydrate
Glycodeoxycholic acid
MFCD00150922
Chemical & Physical Properties
[ Density]:
1.162 g/cm3
[ Boiling Point ]:
655.6ºC at 760 mmHg
[ Molecular Formula ]:
C26H45NO6
[ Molecular Weight ]:
467.63900
[ Flash Point ]:
350.3ºC
[ Exact Mass ]:
467.32500
[ PSA ]:
116.09000
[ LogP ]:
3.92070
[ Index of Refraction ]:
1.546
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB9670000
- CHEMICAL NAME :
- Glycine, N-(3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-yl)-
- CAS REGISTRY NUMBER :
- 360-65-6
- LAST UPDATED :
- 198803
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C26-H43-N-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,323,1970
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MB9670000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Photochem. Photobiol. 88 , 1248, (2012)
Photophysical properties of two widely used antibiotic fluoroquinolone drugs, namely Norfloxacin (NOR) and Ofloxacin (OFL) have been investigated in biomimicking environments formed by bile salts. Exp...
Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using13C nuclear magnetic resonanceAnal. Biochem. 427(1) , 41-8, (2012)
In this work, we develop a methodology to quantitatively follow the solubilization of cholesterol on glycodeoxycholic acid (GDCA) micelles using 13C nuclear magnetic resonance (NMR). The amount of sol...
Effects of glutamine alone on the acute necrotizing pancreatitis in rats.J. Surg. Res. 193(1) , 161-7, (2015)
The effects of the glutamine on the acute pancreatitis are controversial in the clinical and experimental studies. The aim of this study was to investigate the influence of glutamine alone on acute ne...