4-Benzyl-3-(butylamino)-5-sulfamoylbenzoic acid
Names
[ CAS No. ]:
36148-38-6
[ Name ]:
4-Benzyl-3-(butylamino)-5-sulfamoylbenzoic acid
[Synonym ]:
Besunida [INN-Spanish]
Besunida [Spanish]
Besunidum [Latin]
4-Benzyl-3-n-butylamino-5-sulfamylbenzoic acid
Besunidum [INN-Latin]
Besunide
pINN
4-Benzyl-3-butylamino-5-sulfamoylbenzoic acid
Chemical & Physical Properties
[ Density]:
1.297g/cm3
[ Boiling Point ]:
620.3ºC at 760mmHg
[ Molecular Formula ]:
C18H22N2O4S
[ Molecular Weight ]:
362.44300
[ Flash Point ]:
328.9ºC
[ Exact Mass ]:
362.13000
[ PSA ]:
117.87000
[ LogP ]:
4.68910
[ Index of Refraction ]:
1.611
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG3100500
- CHEMICAL NAME :
- Benzoic acid, 3-(aminosulfonyl)-4-benzyl-5-(butylamino)-
- CAS REGISTRY NUMBER :
- 36148-38-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H22-N2-O4-S
- MOLECULAR WEIGHT :
- 362.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 186 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973
Safety Information
[ HS Code ]:
2935009090
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%