Ethylmalonoyl dichloride

Names

[ Name ]:
Ethylmalonoyl dichloride

[Synonym ]:
Ethylpropanedioyl dichloride
MFCD00000736
Ethylmalonoyl dichloride
Ethyl 3-chloro-3-oxopropanoate
ethoxycarbonylacetyl chloride
Carbethoxyethanoyl chloride
Ethyl Maloriyl Chloride
Propanoic acid, 3-chloro-3-oxo-, ethyl ester
AURORA KA-3051
Propanedioyl dichloride, 2-ethyl-
Ethylmalonylchloride
Ethyl (Chloroformyl)acetate
(Chloroformyl)acetic Acid Ethyl Ester
Ethyl 3-oxo-3-chloropropanoate
3-Chloro-3-oxopropionic Acid Ethyl Ester
carboethoxy-acetyl chloride
chlorocarbonylacetic acid ethyl ester
3-chloro-3-oxo-propanoic acid,ethyl ester
ETHYLMALONYLCHLORIDE,TECHNICAL
2-ethoxycarbonylacetyl chloride
ethyl 2-(chlorocarbonyl)acetate
Ethyl chloroformylacetate
Ethylpropandioyldichlorid
ETHYL 3-CHLORO-3-OXOPROPIONATE
EINECS 252-934-5

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
172.4±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₇ClO₃

[ Molecular Weight ]:
150.560

[ Flash Point ]:
65.0±0.0 °C

[ Exact Mass ]:
150.008377

[ PSA ]:
34.14000

[ LogP ]:
1.09

[ Vapour Pressure ]:
1.3±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.431

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
REACTS

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S7-S26-S36/37/39-S45-S36/39

[ RIDADR ]:
UN 3265 8/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted alpha to the oxazole ring.

J. Med. Chem. 36 , 3871, (1993)

The 4,5-diphenyloxazole derivatives 2-4 were previously identified as nonprostanoid prostacyclin (PGI2) mimetics. A series of derivatives of 2-4 bearing substitutents at the carbon atom alpha to the o...

The biosynthesis and secretion of prostate-specific antigen in LNCaP cells.

J. Chem. Res. Synop. , 192, (1994)

Prostate-specific antigen (PSA) has been demonstrated to release the active form of insulin-like growth factor I in vitro (P. Cohen et al., J. Clin. Endocrinol. & Metab., 75: 1046-1053, 1992; P. Cohen...

Synlett , 65, (1993)