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4-Fluoro-2-nitroaniline

Names

[ CAS No. ]:
364-78-3

[ Name ]:
4-Fluoro-2-nitroaniline

[Synonym ]:
MFCD00007830
4-Fluoro-2-nitroaniline
Benzenamine, 4-fluoro-2-nitro-
4-Fluoro-2-nitrobenzeneamine
4-fluoro-2-nitrobenzenamine
EINECS 206-666-0

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
295.1±20.0 °C at 760 mmHg

[ Melting Point ]:
90-94 °C(lit.)

[ Molecular Formula ]:
C6H5FN2O2

[ Molecular Weight ]:
156.115

[ Flash Point ]:
89.4±0.0 °C

[ Exact Mass ]:
156.033508

[ PSA ]:
71.84000

[ LogP ]:
1.94

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.603

[ Water Solubility ]:
INSOLUBLE

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S36/37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921420090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease.

J. Pharmacol. Exp. Ther. 296 , 600-611, (2001)

The diseases of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are characterized by mucus-congested airways. Agents that stimulate the secretion of Cl- are anticipated to facili...

Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: synthesis and biological testing.

Bioorg. Med. Chem. 12(10) , 2625-37, (2004)

Novel 4-arylpiperazin-1-yl-substituted 2,3-dihydro-1H-1,4- and 1H-1,5-benzodiazepines and their aza-analogues were synthesized as debenzoclozapine derivatives for evaluation as potential D4-ligands. W...

Complexes of copper (II), nickel (II) and cobalt (II) with 2-fluoro, 5-nitroaniline and 4-fluoro, 2-nitroaniline. DeVoto G, et al.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 38(7) , 725-728, (1982)


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