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Metipranolol hydrochloride

Names

[ CAS No. ]:
36592-77-5

[ Name ]:
Metipranolol hydrochloride

[Synonym ]:
METIPRANOLOL HYDROCHLORIDE
[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-2,3,6-trimethylphenyl] acetate,hydrochloride
Optipranolol (TN)
UNII-FBW237ALKD
Phenol,4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6-trimethyl-,(+-)-,1-acetate,hydrochloride
Metipranolol HCl

Biological Activity

[Description]:

Metipranolol is a non-selective β adrenergic receptor blocking agent.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Research Areas >> Cardiovascular Disease

[Target]

β adrenergic receptor [1].


[In Vitro]

Metipranolol is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma[1].

[References]

[1]. Wolf S, et al. Acute effect of metipranolol on the retinal circulation. Br J Ophthalmol. 1998 Aug;82(8):892-6.


[Related Small Molecules]

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | Adrenaline | Ivabradine hydrochloride | Prazosin hydrochloride | Clenbuterol hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | pimozide | Sotalol hydrochloride | Carvedilol | Atenolol | Metroprolol succinate

Chemical & Physical Properties

[ Boiling Point ]:
484.5ºC at 760 mmHg

[ Molecular Formula ]:
C17H28ClNO4

[ Molecular Weight ]:
345.86200

[ Flash Point ]:
246.8ºC

[ Exact Mass ]:
345.17100

[ PSA ]:
67.79000

[ LogP ]:
3.46770

[ Storage condition ]:
2-8℃

Related Compounds