isoluminol

Names

[ Name ]:
isoluminol

[Synonym ]:
6-Amino-2,3-dihydro-1,4-phthalazinedione
4-AMINOPHTHALHYDRAZIDE MONOHYDRATE
4-Aminophthaloylhydrazine
Isoluminol [Chemiluminescence reagent]
4-Amino-phthalsaeure-hydrazid
6-amino-2,3-dihydro-phthalazine-1,4-dione
MFCD00010560
6-Amino-2,3-dihydro-phthalazin-1,4-dion
6-Amino-2,3-dihydro-1,4-phthalazinedione,Isoluminol
4-AMINOPHTHALHYDRAZIDE HYDRATE
isoluminol
1,4-Phthalazinedione, 6-amino-2,3-dihydro-
6-Amino-2,3-dihydro-1,4-phthal
(1,2,3,4-tetrahydro-1,4-dioxo-6-phthalazinyl)amine
6-Amino-2,3-dihydrophthalazine-1,4-dione

Biological Activity

[Description]:

7-Amino-4-hydroxyphthalazin-1(2H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
633ºC at 760mmHg

[ Melting Point ]:
300 °C(lit.)

[ Molecular Formula ]:
C₈H₇N₃O₂

[ Molecular Weight ]:
177.160

[ Flash Point ]:
336.7ºC

[ Exact Mass ]:
177.053833

[ PSA ]:
91.74000

[ LogP ]:
-0.71

[ Index of Refraction ]:
1.649

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

H1-antihistamines and oxidative burst of professional phagocytes.

Neuro Endocrinol. Lett. 30 Suppl 1 , 133-6, (2009)

We analysed and compared the effect of five H1-antihistamines on stimulated oxidative burst at extra- and intracellular level of isolated and stimulated human polymorphonuclear leukocytes.Oxidative bu...

A new chemiluminescence paradox: selective inhibition of isoluminol-amplified activity in phagocytes by peptides from annexin AI.

Luminescence 23(3) , 139-43, (2008)

Chemiluminescence systems enhanced by either isoluminol or luminol in combination with a peroxidase are sensitive methods for the detection of reactive oxygen species (ROS) generated by phagocyte NADP...

An attempt to design an isoluminol-hydrogen peroxidase-amplified CL that measures intracellularly produced H2O2 in phagocytes: sensitivity for H2O2 is not high enough to allow detection.

Luminescence 22(5) , 507-10, (2007)

A technique was designed for the determination of hydrogen peroxide release. We found, however, that the isoluminol-amplified chemiluminescence technique is a suitable tool for measuring secretion of ...