4-CHLORO-N-METHYL-3-(METHYLSULFAMO-YL)BENZAMIDE
Names
[ CAS No. ]:
3688-85-5
[ Name ]:
4-CHLORO-N-METHYL-3-(METHYLSULFAMO-YL)BENZAMIDE
[Synonym ]:
4-Chlor-N-methyl-3-(methylsulfamoyl)-benzamid
Tiamizide
Diapamide [USAN]
Vectren
Thiamizide
CI-456
Tiamizid
Tiamizida [INN-Spanish]
Tiamizidum [INN-Latin]
Diapamide
Chemical & Physical Properties
[ Density]:
1.365g/cm3
[ Molecular Formula ]:
C9H11ClN2O3S
[ Molecular Weight ]:
262.71300
[ Exact Mass ]:
262.01800
[ PSA ]:
83.65000
[ LogP ]:
2.47030
[ Index of Refraction ]:
1.554
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV2451800
- CHEMICAL NAME :
- Benzamide, 4-chloro-N-methyl-3-(methylsulfamoyl)-
- CAS REGISTRY NUMBER :
- 3688-85-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H11-Cl-N2-O3-S
- MOLECULAR WEIGHT :
- 262.73
- WISWESSER LINE NOTATION :
- 1MVR DG CSWM1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2580 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 520 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963
Safety Information
[ HS Code ]:
2935009090
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%