Δ7-sterol 5(6)-desaturase

Names

[ CAS No. ]:
37255-37-1

[ Name ]:
Δ7-sterol 5(6)-desaturase

[Synonym ]:
EC 1.14.19.20
lathosterol oxidase
Δ7-sterol Δ5-dehydrogenase
Δ7-sterol 5-desaturase
Δ7-sterol-C5(6)-desaturase
5-DES
SC5DL (gene name)
ERG3 (gene name)

Biological Activity

[Description]:

This enzyme, found in eukaryotic organisms, catalyses the introduction of a double bond between the C5 and C6 carbons of the B ring of Δ7-sterols, to yield the corresponding Δ5,7-sterols. The enzymes from yeast, plants and vertebrates act on avenasterol, episterol, and lathosterol, respectively. The enzyme is located at the endoplasmic reticulum and is membrane bound. Reaction: a Δ7-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ = a Δ5,7-sterol + 2 ferricytochrome b5 + 2 H2O

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds