2,2,2-trifluoroethanaminium chloride

Names

[ CAS No. ]:
373-88-6

[ Name ]:
2,2,2-trifluoroethanaminium chloride

[Synonym ]:
2,2,2-Trifluoroethanamine hydrochloride
Ethylamine, 2,2,2-trifluoro-, hydrochloride (8CI)
EINECS 206-771-1
Ethanamine, 2,2,2-trifluoro-, hydrochloride (1:1)
2,2,2-trifluoroethanamine,hydrochloride
2,2,2-trifluoroethanaminium chloride
2,2,2-Trifluoroethanamine hydrochloride (1:1)
MFCD00012875
2,2,2-TrifluoroethylaMine Hydrochloride
TrifluorethylaminHCL

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
121.9ºC at 760 mmHg

[ Melting Point ]:
220-222 °C (subl.)(lit.)

[ Molecular Formula ]:
C₂H₅ClF₃N

[ Molecular Weight ]:
135.516

[ Flash Point ]:
27.6ºC

[ Exact Mass ]:
135.006256

[ PSA ]:
26.02000

[ LogP ]:
2.00970

[ Index of Refraction ]:
1.3-1.302

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KS0250000

CHEMICAL NAME :: Ethylamine, trifluoro-, hydrochloride

CAS REGISTRY NUMBER :: 373-88-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C2-H4-F3-N.Cl-H

MOLECULAR WEIGHT :: 135.53

WISWESSER LINE NOTATION :: Z1XFFF &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 476 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 11FYAN "Fluorine Chemistry, Volume III. Biological Effects of Organic Fluorides," Simons, J.H., ed., New York, Academic Press, Inc., 1963 Volume(issue)/page/year: 3,81,1963

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;T: Toxic;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36/37-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KS0250000

[ Packaging Group ]:
III

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Aqueous in situ derivatization of carboxylic acids by an ionic carbodiimide and 2,2,2-trifluoroethylamine for electron-capture detection.

J. Chromatogr. A. 1145(1-2) , 241-5, (2007)

We report a technique for the rapid, room temperature derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative. 3-Ethyl-1-[3-(dimethylamino)propyl]carbodiim...