(2-Nitrophenyl)acetic acid

Names

[ Name ]:
(2-Nitrophenyl)acetic acid

[Synonym ]:
MFCD00007190
EINECS 223-128-0
Benzeneacetic acid, 2-nitro-
(2-Nitrophenyl)acetic acid
2-(2-nitrophenyl)acetic acid
2-Nitrophenylacetic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
345.1±17.0 °C at 760 mmHg

[ Melting Point ]:
137-140 °C(lit.)

[ Molecular Formula ]:
C₈H₇NO₄

[ Molecular Weight ]:
181.145

[ Flash Point ]:
155.9±9.4 °C

[ Exact Mass ]:
181.037506

[ PSA ]:
83.12000

[ LogP ]:
1.24

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.598

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AJ1130000

CHEMICAL NAME :: Acetic acid, (o-nitrophenyl)-

CAS REGISTRY NUMBER :: 3740-52-1

BEILSTEIN REFERENCE NO. :: 1959243

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H7-N-O4

MOLECULAR WEIGHT :: 181.16

WISWESSER LINE NOTATION :: WNR B1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 5 mg/disc

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R36/37/38;R68

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AJ1130000

[ HS Code ]:
29163900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Studies on the catalytic behaviour of a cholinesterase-like abzyme in an AOT microemulsion system.

J. Biotechnol. 97(2) , 177-82, (2002)

The hydrolytic activity of a monoclonal catalytic antibody (9A8) (abzyme) with acetylcholinesterase-like activity was investigated in water-in-oil (w/o) microemulsions (reverse micelles) based on sodi...

Molecular mechanism of uncaging CO2 from nitrophenylacetate provides general guidelines for improved ortho-nitrobenzyl cages.

ChemPhysChem 12(11) , 2077-80, (2011)

Femtosecond spectroscopy and quantum chemical calculations provide detailed insights into the specificities of the uncaging mechanism of CO2 from ortho-, meta-, and para-nitrophenylacetate. The emergi...

Determination of the theophylline solubilizer salicylamide-O-acetic acid in serum and urine using high-performance liquid chromatography.

J. Pharm. Biomed. Anal. 3(5) , 469-75, (1985)

A high-performance liquid chromatographic method for the determination of the theophylline solubilizer salicylamide-O-acetic acid has been developed in the range 0.5 to 10 microg/ml for human serum an...